Immiscible solvents in relation to solubility and miscibility.
Solubility is the ability of a solid to dissolve in a liquid. Miscibility refer only to liquids. It is the ability of a liquid to mix and form a homogeneous solution soluble in any proportion.
Immiscibility refer to those liquids that cannot mix to form a homogeneous solution soluble in all proportions. Immiscible solvents are incapable of mixing with another solvent and will separate out into a definite layer. Immiscible solvents cannot blend into or attain homogeneity with another liquid.
These solvents are either miscible or immiscible in each other.
The solvent on left column does not mix with solvents on right column unless otherwise stated.
| SOLVENTS |
Immiscibility |
|---|
| Acetone |
can be mixed with any of the solvents listed in the column at left
|
| Acetonitrile |
cyclohexane, heptane, hexane, pentane, 2,2,4-trimethylpentane |
| carbon tetrachloride |
can be mixed with any of the solvents listed in the column at left
except water |
| chloroform |
can be mixed with any of the solvents listed in the column at left
except water |
| cyclohexane |
acetonitrile, dimethyl formamide, dimethyl sulfoxide, methanol,
water |
| 1,2-dichloroethane |
can be mixed with any of the solvents listed in the column at left
except water |
| dichloromethane |
can be mixed with any of the solvents listed in the column at left
except water |
| diethyl ether |
dimethyl sulfoxide, water |
| dimethyl formamide |
cyclohexane, heptane, hexane, pentane, 2,2,4-trimethylpentane,
|
| dimethyl solfoxide |
cyclohexane, heptane, hexane, pentane, 2,2,4-trimethylpentane,
diethyl ether |
| 1,4-dioxane |
can be mixed with any of the solvents listed in the column at left
|
| ethanol |
can be mixed with any of the solvents listed in the column at left
|
| ethyl acetate |
can be mixed with any of the solvents listed in the column at left
except water |
| heptane |
acetonitrile, dimethyl formamide, dimethyl sulfoxide, methanol,
water
|
| hexane |
acetonitrile, dimethyl formamide, dimethyl sulfoxide, methanol, acetic acid,
water |
| methanol |
cyclohexane, heptane, hexane, pentane, 2,2,4-trimethylpentane |
| methyl-tert-butyl ether |
can be mixed with any of the solvents listed in the column at left
except water |
| pentane |
acetonitrile, dimethyl formamide, dimethyl sulfoxide, methanol,
water, acetic acid |
| 1-propanol |
can be mixed with any of the solvents listed in the column at left
|
| 2-propanol |
can be mixed with any of the solvents listed in the column at left
|
| tetrahydrofuran |
can be mixed with any of the solvents listed in the column at left
|
| toluene |
can be mixed with any of the solvents listed in the column at left
except water |
| 2,2,4-trimethylpentane |
acetonitrile, dimethyl formamide, dimethyl sulfoxide, methanol,
water
|
| water |
carbon tetrachloride, chloroform, cyclohexane, 1,2-dichloroethane,
dichloromethane, diethyl ether, dimethyl formamide, ethyl acetate,
heptane, hexane, methyl-tert-butyl ether, pentane, toluene,
2,2,4-trimethylpentane |
